Tanaka Tetsuro is excited at getting a full scholarship at a new high school, far away from his family. What he does not know is that he will be the only boy in an all girl school, and that there is a girl head-over-heels in love with him, waiting for his arrival. But his special friendship with the very cute and dynamic Asuka also causes him to get into a lot of trouble with the powerful student council leadership, as they are at open war with Asuka and her five friends, a group of super amazon warriors called the Koi Koi Seven.
逐渐习惯了高中生活的前暗黑破坏神少年Fujay Yong Tai（福山润配音）患有中学疾病，在外表和行为上都变得异常正常。然而，也许是命运故意开玩笑，导致他的周围挤满了中学生或潜在患者。
故事发生在位于东京中北部的大岛镇。一个名叫Issey（由Ayama Sasakura配音）的14岁普通女孩和她的妹妹Iseta（由Akira Otsui配音）与年迈的祖父过着相互依赖的生活。尽管生活简单而艰难，但这个家庭最终充满了幸福。
